Division of Molecular Genetics
The Division of Molecular Genetics of the German Cancer Research Center (DKFZ) investigates tumor pathomechanisms in order to better understand the biological behavior of tumors. Our research involves the comprehensive molecular characterization of tumors at the genome, methylome and / or transcriptome level, using microarray technologies and next-generation sequencing of nucleic acids. Candidate genes are subsequently functionally validated in vitro and in vivo. The integration of these data allows the identification of molecular signaling pathways and networks that can serve as targets for targeted cancer therapies. To translate these findings into clinical practice, specific inhibitors are being tested in preclinical models.
Please further information about our research on the DKFZ pages of the Division of Molecular Genetics at the DKFZ.