Treatment of non-malignant blood diseases

The doctors and researchers at the KiTZ have extensive experience in treating non-malignant blood diseases such as anemia, coagulopathies, and blood diseases related to immune defects.

Anemias (from the Greek “lack of blood”) are the most well-known non-cancerous blood diseases. They are marked by a decrease of hemoglobin in the blood. Anemias also affect the red blood cells (erythrocytes) – as opposed to malignant leukemias, in which the white bloods cells are diseased. Due to increased migration from Mediterranean regions, and the Middle East, other erythrocyte diseases are becoming more common, such as the so-called sickle-cell disease or thalassemia. Patients with anemia can find help at the KiTZ – please talk to us.

Three research groups at the KiTZ deal with non-malignant blood diseases. Rare anemias in particular are congenital blood disorders which occur in less than 2.000 people in Germany.

Thalassemia and sickle cell anemia center Rhein-Neckar
In order to respond better to the needs of children and adolescents with hemoglobin diseases, the doctors of the KiTZ founded the Thalassemia and Sickle Cell Anemia Center Rhein-Neckar in cooperation with colleagues of the University Medical Center Mannheim (UMM).

Gene therapy for transfusion-dependent β-thalassemia
The KiTZ is the first center in Germany to treat a form of the rare hereditary disease transfusion-dependent β-thalassemia (TDT) with a new gene therapy.

Consultation "Hemoglobin diseases"
Dr. Joachim Kunz
Tel.: +49 6221 – 564002
E-Mail: joachim.kunz(at)

Oncological and hematological outpatient department:
Registration desk: +49 6221 - 56 8381
Mon - Fr    8.00 am – 3.30 pm

Disorders of the coagulation system can lead to reduced hemostasis (tendency to bleed) or excessive coagulation (increased risk of thrombosis). For the competent and adequate care of children with coagulation disorders – in addition to the necessary experience – a professional all-time available infrastructure is necessary.

In interdisciplinary cooperation, we treat children and adolescents with congenital and acquired disorders of blood clotting (e.g. hemophilia, von-Willebrand-Jürgens syndrome, platelet dysfunction).

Upon finding unusual coagulation levels in a patient, we immediately investigate. Sometimes, multiple blood tests or so-called stimulation tests are necessary to identify the cause of the coagulation disorder. Many patients present with abnormal blood coagulation determined during the run-up to surgery. We clarify this, contact the surgeons, and take care of all necessary security measures in connection with the upcoming surgery.

We are happy to assist external colleagues when it comes to finding the right method for dealing with the coagulation disorder.

A center for the treatment of haemophiliac children and adolescents

Our department is a regional center for the treatment of haemophiliac children and adolescents. Specialists  for consultation are available at all times. Together with all other clinics and institutes of the Heidelberg University Hospital we incorporate all necessary diagnostic and therapeutic facilities. Through many years of good cooperation with the Hemophilia Center for Adults at the SRH Clinic Heidelberg we can provide seamless care during progression into adulthood.

Consultation "Coagulation"
Dr. Wolfgang Behnisch
Tel.: +49 6221 – 56 4002
E-Mail: wolfgang.behnisch(at)

Oncological and hematological outpatient department:
Registration desk: +49 6221 – 56 8381
Mon – Fr    8.00 am – 3.30 pm

Immune defects denote illnesses impairing the immune system’s function due to a genetic defects from birth.
In order to diagnose blood diseases as quickly as possible, the Center for Child and Youth Medicine has established a child hematology laboratory consolidating information and facilitating faster diagnoses.

Consultation "Immune defects"
Prof Dr. Andreas Kulozik
Tel.: +49 6221 – 56 4500
E-Mail: andreas.kulozik(at)

PD Dr. med. Johann Greil
Tel.: +49 6221 – 56 4002 or – 56 5054
E-Mail: johann.greil(at)

Oncological and hematological outpatient department:
Registration desk: +49 6221 – 56 8381
Mon – Fr    8.00 am – 3.30 pm