When chemotherapy fails: A molecular Achilles heel in bone and soft-tissue cancer

 

Scientists at the Hopp Children’s Cancer Center Heidelberg (KiTZ) and the German Cancer Research Center (DKFZ), working with other groups of...

Better treatment opportunities for children with cancer in Europe

 

Today at the Dutch Embassy in Berlin, in the presence of Queen Máxima of the Netherlands, after whom the Princess Máxima Center for Pediatric Oncology...

What drives aggressiveness in childhood neuroblastoma?

 

Scientists from the Hopp Children’s Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ) and the University of Heidelberg may...

Stefan Pfister receives the Léopold Griffuel Award for his research on childhood cancer

 

Stefan Pfister, a director of the Hopp Children’s Cancer Center Heidelberg (KiTZ), a department head at the German Cancer Research Center (DKFZ) and a...

Some childhood tumors start in early pregnancy

 

Neuroblastoma is one of the most common solid childhood tumors, and forms even before the baby is born. In high-risk patients, certain genetic...

Disease progression in childhood cancer: Lengthening of telomeres promotes relapse

 

Neuroblastoma can spread relentlessly or shrink spontaneously. Scientists from the Hopp Children’s Cancer Center Heidelberg (KiTZ), the German Cancer...

A defect with serious consequences: Epigenetic reprogramming turns neural stem cells into drivers of childhood brain tumors

 

During embryonic brain development, neural stem cells pass through a series of strictly regulated development phases. A mutation in a protein that...

Improving survival in aggressive childhood cancers

 

A new drug combination could help improve survival and quality of life for some children with a particularly aggressive form of brain tumour,...

Childhood cancer: Molecular super-enhancers determine progression of neuroblastomas

 

Childhood neuroblastomas display extreme differences in the way they develop: they can shrink spontaneously or spread aggressively to healthy tissue....

Personalized drug screens could guide treatment for children with brain cancer

 

Scientists at Sanford Burnham Prebys Medical Discovery Institute, University of California San Diego School of Medicine and Hopp Children’s Cancer...